Zyloprim is a tablet the effect of which appears due to the mechanism of action of its basic component called Allopurinol. This medicine is prescribed as a treatment of hyperuricemia, primary and secondary gout, urolithiasis with the formation of urinary calculi, hemoblastoma, cytostatic and radiation therapy of tumors, psoriasis, traumatic toxicosis. It is used as a corticosteroid therapy for the prevention of urinary acid nephropathy, malignant neoplasms and congenital disorders of purine metabolism in children.
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Zyloprim product description
Drug uses
Zyloprim belongs to the group of drugs, called anti-uricaemic agents. Zyloprim helps stabilize uric acid levels in people with such common disease. like gout, and some other rare pathological conditions, including Lesch-Nyhan syndrome.
Therapeutic effects of Zyloprim and its active metabolites include dissolution of uric acid salts (urates) in the internal organs, skin, joints, bones, and any other body part. Furthermore, Zyloprim effectively dissolves and prevents kidney stones reformation.
Zyloprim can be used to prevent the diseases of joints and kidneys in frequent relapses of urolithiasis and gout. The range of daily Zyloprim doses for adults ranges from 100 mg to 600 mg of Zyloprim per day. The total daily dose of Zyloprim should be increased to 900 mg in rare cases.
Missed dose
Zyloprim is recommended to be taken every day at the same time, like any other anti-uricaemic drugs. If you skipped a Zyloprim dose in the morning, you can take it during the day.
Usually, simultaneous intake of two Allopurinol daily doses causes no overdose, however, this dosing regimen does not increase the treatment efficacy.
The people with renal dysfunction should take the minimum therapeutic doses of Zyloprim. Pills should be taken at an interval of about 24 hours.
More information
Zyloprim is one of the few anti-uricaemic agents that can be prescribed to pregnant women. Zyloprim should only be used during pregnancy, if alternative therapies turn to be ineffective, or in intra-renal diseases.
Storage
Zyloprim should be stored in the original container (package), at room temperature below 30°C. Keep the container tightly closed to protect Zyloprim tablets from moisture.
Zyloprim safety information
Warnings
Zyloprim may cause allergic skin reactions in the patients with individual hypersensitivity to the drugs of xanthine oxidase inhibitors group. You should discontinue Zyloprim, if you have any symptoms of adverse skin reactions.
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Side effects
Most often, Zyloprim causes undesirable skin reactions. Less commonly Zyloprim adverse effects manifest from the gastrointestinal system.
- You can use anti-inflammatory drugs from the corticosteroids group for the management of mild to moderate cutaneous side-effects.
- Zyloprim tablets are recommended to be taken after main meals, if they cause nausea or vomiting.
You should stop using Zyloprim, if you notice severe side effects or allergic reactions. The patients with a history of mild allergy to Zyloprim can resume using this drug in low doses, only when all skin disorder symptoms disappear.
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