Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
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The medicine is a selective inhibitor of components such as 3-hydroxy-3-methylglutaryl coenzyme a-reductase. They convert 3-hydroxy-3-methylglutaryl coenzyme and malonic acid, which prevents the formation and accumulation of sterols. The pills reduce the level of cholesterol and lipoproteins in the blood plasma
Product Description
The pills help to synthesize cholesterol in the liver and to create a large number of lipoprotein receptors with low density. Such actions lead to increased capture and catabolism of lipoproteins, which have a low density. The tablets make levels of total cholesterol and lipoproteins, which have light density and triglycerides lower. They contribute to the formation of a high cholesterol level.
The remedy is quickly absorbed after taking it. The highest concentration of its components in blood is reached after one to two hours. The higher the dose, the higher the degree of absorption. The pills connect with blood plasma proteins in approximately 98 %. They also form derivatives and beta-oxidation. The remedy is excreted from the organism with bile. The average period of excretion of the components lasts approximately fourteen hours.
Safety Information
There is the infrequent occurrence of rhabdomyolysis which is accompanied by acute renal failure when using this drug or another that belongs to the same category. Any violations of kidney function in the history may lead to the development of rhabdomyolysis. Under such circumstances, people must undergo a thorough examination to identify violations of the skeletal muscles. Tablets like other drugs from the group of statins can sometimes lead to myopathy. It manifests in muscle weakness, a high rate of creatine phosphokinase which is ten times higher than its normal value. If the drug is used simultaneously with atorvastatin or such drugs as clarithromycin, Itraconazole, there may be a high risk of myopathy or rhabdomyolysis.
It is recommended to take a pill of ten or twenty mg.per days for those who have dyslipidemia. People who have high cholesterol and who require a low density of lipoproteins should take 40 mg. once a day. The daily rate of the drug can range from 10 to 80 mg. Tablets can be taken at any time and regardless of food intake. The initial dose of tablets is selected by the doctor individually. Once the treatment has started, it is necessary to check lipid levels within two to four weeks and change their dose to the desired level.
For children from 10 to 17 years, doctors prescribe the dose of 10 mg.per day. The maximum dose is 20 mg. per day and it depends on the point of treatment.
Side Effects
Among the adverse reactions, the most common are such as:
● Chest pain, swelling on the face, general weakness, negative reactions to light, swelling on the body, feeling of malaise;
● In the nervous system there are such adverse events as drowsiness, loss of desire to sleep, dizziness in the head, emotional instability, disturbed coordination of movements, depression, cognitive disorders such as bad memory, and its loss;
● In the intestinal and gastric tract there are such undesired effects as gastroenteritis, duodenal ulcer, hepatitis, diarrhea, constipation, abdominal pain;
In the skeletal system and in the muscular system, there may be increased muscle fatigue, pain in the neck, in the joints, in the back.
Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.
Viagra Professional - Advantage of Professional Viagra from usual Viagra is that it works twice longer (6 - 8 hours) and has a stronger effect. Strengthens desire, improves brightness of sexual feelings and increases duration of sexual intercourse.
Viagra Oral Jelly - a new formula of the drug Viagra. Sildenafil - 100 mg. It is prescribed for men with a weak potentiality. Helps to recover libido and to improve sexual activity. Accelerates process of excitement of reproductive system. It makes erection brighter. Considerably increases duration of sexual intercourse. Besides, drug has various pleasant tastes, it is convenient to carry in a pocket or in a purse. Hurry to try it!
Arcoxia - analgesic and anti-inflammatory drug of a group of highly selective cyclooxygenase-2 inhibitors. The drug has anti-inflammatory, analgesic and antipyretic effect.
Danazol is used in endometriosis (with concomitant infertility), benign neoplasms of the breast (fibrocystic mastopathy), primary menorrhagia, premenstrual syndrome, primary premature puberty, gynecomastia.
Detrol is taken in case of bladder hyperactivity, shown by frequent imperative desires to urination or urine incontience. Reduces contractile function of bladder and reduces salivation. Causes incomplete bladder emptying, increases quantity of a residual urine and reduces detruzor pressure.
Peripheral vasodilator with predominant effect on venous vessels. Reduces the need for myocardium in oxygen by reducing preload and afterload (reduces the end diastolic volume of the LV and reduces the systolic tension of its walls). Has the coronary dilatation effect. Reduces blood flow to the right atrium, helps to reduce pressure in the "small" circle of blood circulation and regression of symptoms with pulmonary edema. Promotes redistribution of coronary blood flow in the area with reduced blood circulation. Increases tolerance to physical activity in patients with IHD, angina pectoris.
Kemadrin is a medicinal substance similar in its effect to atropine; It is used to reduce tremor and rigidity of muscles in Parkinsonism.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
A drug for the prevention and treatment of HIV infection. An antiviral agent, which competitively blocks the reverse transcriptase and selectively inhibits the replication of viral DNA.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
