Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
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Endep Product Description
Drug Uses
Endep is a tricyclic antidepressant with a sedative activity. The mechanism of this antidepressant action is based on the reuptake inhibition of norepinephrine and serotonin (chemicals that affect mood and well-being).
Clinical studies have shown that the anti-cholinergic properties of Endep allow using this antidepressant in the treatment of enuresis (in the absence of organic pathology).
Endep has a powerful antidepressant, sedative and anxiolytic effect, and can be prescribed to adolescents of 18 years of age and older, adults and elderly patients for the treatment of major depression. Endep use in children aged 6 years and older is approved only for the treatment of nocturnal enuresis, and is not recommended for the depression treatment.
The recommended initial Endep dose for the antidepressant therapy is 75 mg per day for adults, divided into several intakes. If necessary, the daily dose of this antidepressant may be increased to 200mg.
The daily dose of Endep for the treatment of nocturnal enuresis should be selected based on the child's age. The children under 6 years of age are usually administered with Endep 10mg immediately before going to bed. The children of 6 to 10 years are recommended to take 10 to 20 mg of Endep per day. Adolescents of 11 to 16 years are prescribed with 25 to 50 mg of the drug for the treatment of nocturnal enuresis.
Missed Dose
If you take several Endep doses a day, and incidentally miss a dose, take it on the same day as soon as possible, but only if there is a lot of time till your next dose of this antidepressant. If you’ve missed a daily dose of Endep, you can take it in the same evening before going to bed. Do not use antidepressant Endep during waking hours or two doses together.
More Information
The elderly patients (65 years and older) are usually recommended to use low-doses of antidepressant Endep for the depression treatment. The daily dose of 50 mg (one tablet Endep 25 mg in the morning and one in the evening) is usually sufficient to take control of depression symptoms in the patients of this age group.
Storage
The antidepressant Endep should be kept in original tightly closed package at controlled room temperature below 25°C. Endep tablets must be protected from heat and moisture.
Endep Safety Information
Warnings
At the initial stage of major depression treatment with the antidepressant Endep, it may cause a sharp deterioration in some symptoms, such as mood disorders or suicidal thoughts. These symptoms usually disappear during further use of this antidepressant. Young adults aged 18 to 24 years are especially susceptible to such Endep action.
Disclaimer
Information about depressive illness, presented in this Endep review, is intended as an additional source of information and can not serve for replacing the medical advice or consultation of a psychologist or a psychiatrist. The online pharmacy reserves the right not to be responsible for any kind of harm, loss or damage, incurred from use of information about the antidepressant Endep.
Endep Side Effects
Endep tablets are generally well tolerated. This antidepressant may cause such adverse events as dizziness, skin rash, delusions, urticaria, urinary disorders, fatigue, increased appetite, weight changes, vomiting, peculiar taste, hallucinations, tinnitus, and constipation. Abrupt Endep cessation is not desirable, because it can lead to irritability, headache, sleep disturbance, restlessness, nightmares, nausea, malaise. The probability of paralytic ileus is higher in elderly patients than in people of other age groups, using Endep.
Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Cialis Oral Jelly (Orange) - a new formula of Cialis which you can have, without washing down with water. Against background of ordinary drug it differs in increased influence speed. It is prescribed for improvement of sexual endurance of men during intimate proximity. It simplifies the excitative process of penis and strengthens erection. Noticeably increases duration of sexual intercourse. Besides, the drug possesses a pleasant orange flavor.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Danazol is used in endometriosis (with concomitant infertility), benign neoplasms of the breast (fibrocystic mastopathy), primary menorrhagia, premenstrual syndrome, primary premature puberty, gynecomastia.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Fluoxetine is an antidepressant group of selective serotonin reuptake inhibitors. It has a timoanaleptic and stimulating effect. It is used for depression of various genesis, obsessive-compulsive disorders, bulimic neuroses.
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Nootropil improves cognitive processes, memory, attention, and mental performance.
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The drug has a thymoleptic and anxiolytic effect. Prescribed for the treatment of depressions of various origins, enuresis including the night one.
Tenorminis a cardioselective beta-adrenoblocker. It is based on a substance called Atenolol, which blocks nerve impulses, which leads to a decrease in the frequency and strength of the heartbeat. Atenolol has antihypertensive (lowers pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) by action.
Tofranil is a drug that is very sensitive to the form of depressive disorder (glycoem depressive disorder, depressive phase of bipolar infections, depressive disorder, migraine, depression, dysthymia;
Vastarel - the main substance of the drug is trimetazidine, which is used for the prevention of angina attacks in IHD, as well as in vertigo caused by violations of cerebral circulation, Meniere's disease, noise in the ears. It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly associated with its antioxidant and antihypoxic properties and cytoprotective effects on the function of cardiomyocytes.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
Zoloft is an antidepresant stopping the reuptake of serotonin, which is performed by the neurons that isolated it. As a result, the concentration of the neurotransmitter increases in the synaptic cleft and the main cause of depressive states, the serotonin deficiency, is eliminated.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Shallaki offers a herbal cure for sore joints and is based on an extract from Boswellia serrate. Completely natural origin of the medicine guarantees its safety and pure benefits for the body. It is a powerful auxiliary remedy applied in the treatment of arthritis as well as prevention of joint conditions. Shallaki alleviates pain and swelling in areas of inflammation and lowers the overall level of triglyceride and cholesterol with high efficiency. Its health-promoting behavior makes it a great aid for weight reduction.
Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Product description
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