Prednisone - is a drug from the group of hormones of the adrenal cortex (glucocorticosteroids). It contains prednisolone as the main substance. It is prescribed to patients who suffer from: Bechterew's disease, inflammatory changes in the spinal cord and membranes, non-infectious arthritis, edematous processes of the vertebrae and its structures, osteoarthrosis, severe soreness in the spine, spinal and nerve injuries of the spine, osteochondrosis.
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Product description
Prednisone is a synthetic corticosteroids used for the treatment of rheumatic diseases, severe allergies, various inflammatory conditions and leukemia. Assigned inside; The side effects are the same as in cortisone. Prednisone is a drug from the group of hormones of the adrenal cortex (glucocorticosteroids). It contains the substance prednisolone.
Indications
Prednisone is prescribed to patients according to the following indications:
- Bechterew's disease.
- Inflammation of the spinal cord and membranes.
- Non-infectious arthritis.
- Edematous processes of vertebrae and its structures.
- Osteoarthritis.
- Pronounced soreness in the spine.
- Injuries to the joints and nerves of the spine.
- Osteochondrosis.
- Absence of efficiency from treatment of a backbone other medicines.
- Hypertonic disease.
- Disease of Itenko-Cushing.
- Allergy to the drug and its components.
- Tuberculosis.
- Nephritis.
- Pregnancy (especially up to 12 weeks).
- Lactation period.
- Obesity.
- Increased brittleness of bones.
- Increased body hair in women.
- Violation of the menstrual cycle.
- Ulcers in the digestive tract.
- Increase in blood sugar.
- Violation of the sexual function.
- Adrenal insufficiency.
Prednisone should be taken orally, swallowing a whole and with enough water. Initially, the drug should be taken at 20-30 mg per day until the therapeutic effect (improving the patient's condition). Then gradually reduce the dosage to 5-10 mg per day. In extreme cases, the initial dosage can be increased to 50-100 mg per day, and up to 15 mg per day. The maximum daily dosage is 100 mg, single dose is 15 mg.
The course of treatment is individual and varies from 1 week to several months.
Safety information
The risk of overdose increases with prolonged use. Symptoms of overdose: increased blood pressure, peripheral edema, increased side effects of the drug. Treatment of acute overdose: immediate gastric lavage or induction of vomiting, no specific antidote was found. Treatment of chronic overdose: should reduce the dose of the drug.
The medicine should be stored in a place protected from light.
Contraindications
Prednisone is contraindicated in the following diseases:
During pregnancy this remedy can be appointed very rarely, as the impact on fetus can not be predictable. Prednisone must be abandoned during the period of lactation.
The drug is prescribed only under the strict supervision of a doctor and in extreme cases for children from 3 years.
Alcoholic drinks do not have an influence on the effect from Prednisone.
Interaction with other substances:
The drug reduces the effectiveness of insulin, oral hypoglycemic and hypotensive drugs, anticoagulants;
Reduces the concentration of salicylates in the blood;
Reduces the concentration of praziquantel in the blood serum.
Rifampicin, phenytoin, barbiturates weaken the effect of prednisone;
Hormonal contraceptives increase its effectiveness.
Side effects
Among the most common side effects of Prednisone can be identified:
- Obesity.
- Increased brittleness of bones.
- Increased body hair in women.
- Violation of the menstrual cycle.
- Ulcers in the digestive tract.
- Increase in blood sugar.
- Violation of the sexual function.
- Adrenal insufficiency.
If such symptoms occur, it is necessary to take symptomatic medications, as far as possible to reduce the dosage of Prednisone as much as possible or to cancel its reception.
Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.
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Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Antabuse - the medicine for treatment of alcoholism. The effect of medicine is implemented due to blockade of acetaldehydehydrogenaz which takes part in ethanol metabolism in consequence of which rises the level of acetaldehyde which causes a number of negative symptoms (including hot flashes, hyperemia of face, vomiting, tachycardia and increase in pressure). These effects arising after alcohol intake lead to development of cause-effect relations and rejections of alcohol intake. Thus, the patient has a conditioned-reflex disgust for a smell and taste of alcohol.
Betapace - beta adrenoblocker, antiarrhytmic medicine. It is taken for treatment of ventricular arrhythmia, tachycardia, supraventricular arrhythmia, tachycardia at thyrotoxicosis, angina of effort, especially at combination with tachyarrhythmias, arterial hypertension, hypertrophic cardiomyopathy, prolapse of the mitral valve, prevention and treatment of myocardial infarction at stable condition of the patient.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Cardizem, derivative benzothiazepine, has anti-anginal, antiarrhytmic and hypotensive effect. It is prescribed at arterial hypertension: after myocardial infarction, at patients with accompanying stenocardia when beta adrenoblockers, are contraindicative at patients with diabetic nephropathy, in cases when ACE inhibitors are contraindicated; angina of effort, Prinzmetal's angina; prevention of a coronary spasm when carrying out a coronary angiography or operation of aortocoronary shunting.
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
BCCC; a derivative of diphenylalkylamine. Has antianginal, anti-arrhythmic and hypotensive effect. The antianginal effect is associated with both direct action on the myocardium and with the effect on peripheral hemodynamics. It is prescribed with stenocardia, supraventricular tachycardia, sinus tachycardia, ciliary tachyarrhythmia, atrial flutter, atrial extrasystole, arterial hypertension, GOKMP, primary hypertension in the "small" circle of the circulation.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
An antispasmodic drug, which removes pain and reduces the tone of smooth muscles: gastrointestinal tract, biliary tract, uterus, it also relaxes the detrusor (direct antispasmodic and m-anticholinergic effect). Increases bladder capacity, reduces the frequency of detrusor contractions, hinders urination. Well tolerated when appointed for a long term. Used in neurogenic bladder (including detrusor hyperreflexia, multiple sclerosis or spina bifida), urinary incontinence (of idiopathic origin), nocturnal enuresis (in children older than 5 years).
A nonsteroidal anti-inflammatory drug that has anti-inflammatory, analgesic, antipyretic action. Prescribed for inflammatory diseases of the musculoskeletal system (rheumatoid, gouty arthritis, arthritis, ankylosing spondylitis), pain syndrome (ossalgia, neuralgia, myalgia, arthralgia, sciatica, headache, dental pain, childbirth), for orthopedic surgery, cancer, algodismenorrhea, febrile syndrome.
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Starlix - an oral synthetic hypoglycemic drug. A medicine based on nateglinide for the treatment of diabetes, which helps to control blood sugar levels. This medicine helps your body to react better to the insulin produced by your pancreas.
Starlix is used in conjunction with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Verapamil is a calcium channel blocker, it treats high blood pressure relaxing and widening blood vessels.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
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Avodart – special medical remedy, also named Dutasteride, refers to urological drugs. A considerable number of men who are at the age of fifty and older address a urologist for the occurrence of a micturition disorder due to benign prostatic hyperplasia. Avodart capsules help to overcome this malady.
Atorlip-5 is a drug which purpose is to lower the level of so-called bad cholesterol in the human organism. Its amount is identified due to the blood testing. The accumulation of low-density lipoprotein can lead to atherosclerosis. As the result, arteries are getting narrow causing cardiovascular complications as strokes, heart attacks, hypertonia, and peripheral artery disease. Liver fat can be also reduced thanks to the drugs. The other benefit is that the medicine increases the level of high-density lipoprotein.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
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Tadalafil is phosphodiesterase type 5 inhibitor and has similar actions to the other phosphodiesterase type 5 inhibitors such as Sildenafil Citrate.
Zhewitra 20 mg is made of Sunrise remedies which is a generic pill of the patent medicine Levitra. It contains Vardenafil HCL in the composition of 20 mg. In India, the sunrise cure is a fast-growing manufacturer, exporter & provider of Pharmaceutical and Herbal Formulations including Herbal Remedies, Cosmetics & Ayurvedic devising.
It also deals in Allopathic formulations in the form of pills, medicine, water, and Topical sections as per international acceptance levels.
Dapoxetine is used as a treatment for premature ejaculation.