Danazol is used in endometriosis (with concomitant infertility), benign neoplasms of the breast (fibrocystic mastopathy), primary menorrhagia, premenstrual syndrome, primary premature puberty, gynecomastia.
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Danazol product description
Danazol belongs to the group of drugs intended for the treatment of sexual/urinary diseases and sex hormone preparations.
The composition includes Danazol - a means that modulates the work of the reproductive system.
Danazol inhibits the production of gonadotropic hormones (follicle-stimulating and luteotropic) by the pituitary gland. Gonadotropin deficiency slows the work of ovaries and ovulation, reduces the concentration of estrogen in the body, endometrial atrophy occurs. With endometriosis, the medication damages normal and ectopic areas; reduces the area of damaged areas and reduces pain. Under the influence of the drug, proliferation of erythrocytes, the development of immunoglobulins and autoantibodies is reduced. In case of mastopathy with fibrocystic formations, Danazol helps to reduce the size of the nodes or complete their dissolution with the elimination of pain and discomfort. By increasing the content of the C1-esterase inhibitor, Danazol helps with hereditary angioedema. Pharmacological action of the drug is reversible. In case of using the high tolerated doses, Danazol may have a weak androgenic effect and may be accompanied by anabolism.
Danazol safety information
Danazol is forbidden for people with allergies to danazol and intolerance to other capsule components. The drug is contraindicated if the patient has porphyria, glucose-galactose malabsorption, heart failure, kidney and liver, bleeding from the genital organs without establishing the cause, acute thrombosis and thromboembolic disease, lactose deficiency. Danazol is not allowed for oncological patients with androgen-dependent tumors, breast cancer. Capsules are not allowed for children under 18 years of age. It is possible to treat Danazol with liver, kidney, heart and vascular diseases, diabetes mellitus, hypertension, migraine, polycythemia, epilepsy, dyslipidemia, with persistent androgenic reactions to sex hormone therapy in the anamnesis, with caution. Caution should be taken while consuming medication in case of violation of plasma mechanisms of hemostasis and any other conditions that can worsen if the water-electrolyte balance is disturbed. It is forbidden to use Danazol for the medical care of pregnant and lactating women. During therapy, non-hormonal methods of contraception should be used.
Danazol side effects
Often, with the use of capsules, some patients may experience the following adverse reactions: seborrhea, acne, emotional lability, weight gain, hirsutism, alopecia, voice coarsening, increased appetite, menstrual irregularity, mucous hemorrhagic discharge between menstruation, amenorrhea, vaginal dryness, anxiety, changes in libido, irritation of the vaginal mucosa , hot flashes, headache, hypersensitivity to insulin, decreased glucose tolerance, increased HDL concentration, decreased thyroxine content, rash, fever, facial edema and Charter, photosensitivity, pain in the back, extremities and joints, muscle spasms, tremors, fasciculation, depression, nervousness, nausea. Infrequent use of Danazol can cause a decrease in the mammary glands, urticaria, an increase in the activity of serum transaminases. Rarely, tachycardia, pancreatitis, visual impairment, clitoral hypertrophy, fluid retention in the body, decreased spermatogenesis, inflammation of the erythematous nodes, leukopenia, skin pigmentation disorder, exfoliative dermatitis, exudative erythema multiforme, cholestatic jaundice, hypertension, palpitation, thrombotic complications, an increase in the content of red blood cells and platelets, dizziness, polycythemia, increased intracranial pressure, thrombocytopenic benign adenoma of the liver, weakness. Very rarely, Danazol therapy provokes myocardial infarction, epilepsy weighting, migraine attacks, eosinophilia, splenic peliosis, malignant tumor and liver hemorrhage, hematuria, epigastric pain, carpal tunnel syndrome, interstitial pneumonia.
Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Cialis Oral Jelly (Orange) - a new formula of Cialis which you can have, without washing down with water. Against background of ordinary drug it differs in increased influence speed. It is prescribed for improvement of sexual endurance of men during intimate proximity. It simplifies the excitative process of penis and strengthens erection. Noticeably increases duration of sexual intercourse. Besides, the drug possesses a pleasant orange flavor.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Fluoxetine is an antidepressant group of selective serotonin reuptake inhibitors. It has a timoanaleptic and stimulating effect. It is used for depression of various genesis, obsessive-compulsive disorders, bulimic neuroses.
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Nootropil improves cognitive processes, memory, attention, and mental performance.
Nootropilum affects the CNS, by changing the speed of propagation of the excitation in the brain, improves metabolic processes in nerve cells, improves by acting on the rheological characteristics of blood and causing no vasodilatory action.
The drug has a thymoleptic and anxiolytic effect. Prescribed for the treatment of depressions of various origins, enuresis including the night one.
Tenorminis a cardioselective beta-adrenoblocker. It is based on a substance called Atenolol, which blocks nerve impulses, which leads to a decrease in the frequency and strength of the heartbeat. Atenolol has antihypertensive (lowers pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) by action.
Tofranil is a drug that is very sensitive to the form of depressive disorder (glycoem depressive disorder, depressive phase of bipolar infections, depressive disorder, migraine, depression, dysthymia;
Vastarel - the main substance of the drug is trimetazidine, which is used for the prevention of angina attacks in IHD, as well as in vertigo caused by violations of cerebral circulation, Meniere's disease, noise in the ears. It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly associated with its antioxidant and antihypoxic properties and cytoprotective effects on the function of cardiomyocytes.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Shallaki offers a herbal cure for sore joints and is based on an extract from Boswellia serrate. Completely natural origin of the medicine guarantees its safety and pure benefits for the body. It is a powerful auxiliary remedy applied in the treatment of arthritis as well as prevention of joint conditions. Shallaki alleviates pain and swelling in areas of inflammation and lowers the overall level of triglyceride and cholesterol with high efficiency. Its health-promoting behavior makes it a great aid for weight reduction.
Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Product description
Alfacip is an active metabolite of Alfacip, which performs important functions in regulation of the calcium balance and the bone metabolism. (Hypocalcemia; Osteodystrophy; secondary hyperparathyroidism;)
