Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
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Actos product description
Drug uses
Actos pills do not help to produce insulin, decrease the insulin-dependent glucose level, and are used to control type 2 diabetes mellitus in people above 18 year old. The drug should be taken with a special diet (low in simple carbohydrates).
Actos pills provide an antihyperglycemic effect while taken alone, however, are often indicated with Sulfonylurea, Metformin, or other pills to treat diabetes. At the beginning of diabetes treatment, one Actos pill of 15mg or 30mg per day is to be taken.
In case of heart diseases or combination therapy of Actos with insulin in elderly patients, first the minimum dosage of 15mg should be used. Based on the patient’s tolerability, the dosage may be increased to a maximum of 45mg per day.
Missed dose
If you revealed that a dose of Actos was just missed, take it as soon as possible. If you remember it on the next day, don’t double it, just skip it, and adhere to your usual Actos intake schedule.
More information
Actos pills provide a steady state within the first week of the treatment. In the first 7 days, try to minimize consumption of simple carbohydrates, and to comply with the recommended dosing schedule.
Storage
Antidiabetic drug Actos should be stored at controlled room temperature of 25°C in a tightly closed container. Do not expose to direct sunlight, protect from moisture.
Actos safety information
Warnings
Actos pills are recommended for long-term control over the blood glucose level and should be taken with caution while combined with other drugs affecting glucose metabolism (e.g., Gemfibrozil). In case of combination of two drugs, dosing regimen of one of them should be changed. During use of Actos pills, people with chronic diseases should regularly assess the balance of advantages and risks. Dosage may require to be changed in mild to moderate heart diseases. In case of liver failure, the intake of antihyperglycemic drug Actos should be stopped.
Disclaimer
This review on Actos represents an important part, not full information about the oral hypoglycemic therapy. Therefore, this review should not be considered as consultation with the therapist or diabetologist. In using Actos review as a source of information, you agree that the online pharmacy is not responsible for any of your decisions and actions taken or not taken due to your use of any information on this hypoglycemic drug.
Actos Side effects
Actos adverse effects are reported as mild and transient like any other antidiabetic drugs. Just about 4% of patients taking Actos were reported to stop the drug intake because of adverse effects.
In most cases treatment is stopped due to pulmonary diseases (sinusitis, myalgia, and pharyngitis), visual disturbance and headache. These adverse effects are observed in patients taking the oral antidiabetic agent over 20 weeks.
The patients treated with Actos for over 24 months are mainly reported to have disorders of cardiac function leading to the therapy discontinuation. Chronic heart failure was observed in the patients taking Actos as seen from the postmarketing experience. And it has developed in the patients with no history of heart disorders before they started the medication intake.
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