Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.
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Imuran Product Description
Drug Uses
Imuran is an immunosuppressive agent used for the suppression of immune responses in the treatment of autoimmune diseases or after organ transplantation. Imuran tablets can be used alone, or as a part of combined immunomodulatory therapy.
As an immunosuppressive antimetabolite, Imuran is approved as:
- Prevention of rejection of transplanted organs and improved survival after organ transplantation (including for medical management of renal, cardiac and hepatic transplant recipients).
- Management of active, severe, inflammatory and chronic autoimmune diseases of joints, skin, skeletal muscles, blood cells, arteries, liver and other organs and body systems.
Imuran maintenance dose to prevent transplant rejection ranges from 1mg to 4mg (once a day). The maintenance daily doses of Imuran for patients with autoimmune diseases vary from 1mg to 3mg (as a single or two divided doses).
Missed dose
If you take Imuran several times a day and skip a regular dose, take it as soon as you remember. Do not double Imuran dose and do not take extra immunosuppressive drugs to make up the missed dose.
More Information
To prevent transplant rejection, Imuran can be used together with other immunosuppressive agents. For symptomatic treatment of autoimmune diseases, Imuran can be used together with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs).
Storage
Imuran tablets should be protected from direct sunlight and stored in a dry place, at room temperature not exceeding 30°C.
Imuran Safety Information
Warnings
Drugs suppressing immune responses (such as, Imuran) may increase the risk of developing malignancies. Patients with high risk of malignancies should be prescribed with Imuran only if the benefits of immunosuppressive therapy outweigh the potential risks.
Disclaimer
Data about immunosuppressive therapy represented in this Imuran review is intended only for general information. This information in no case does not constitute an offer of a substitute for the immunologist’s professional medical advice or diagnosis of immune diseases. The online pharmacy shall not be held responsible for any damages resulting from the use of information about transplantation, autoimmune diseases and Imuran.
Imuran Side Effects
Imuran adverse reactions are reversible and disappear when decreasing the dose or duration of immunosuppressive therapy. The most severe adverse reactions of Imuran are hematologic and gastrointestinal disorders, such as leucopenia, infection, anemia, nausea, vomiting, hepatic toxicity, diarrhea, fever, malaise, vasculitis or muscle pain. Less often, Imuran may cause skin rashes, hair loss, fever, joint pain, steatorrhea, infections (e.g. viral, fungal and bacterial) or exanthem.
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Cialis is a latest medicine for treatment of disturbances of erection at men. Cialis feature is its high-speed performance (30 minutes) and a long-term effect (up to 36 hours). In this regard you can choose the moment which is most suitable for sexual intercourse, having accepted a drug in advance. It is possible to take Cialis in the morning and to be ready even next day. Active ingredient - Tadalafil, the recommended dosage - 20 mg.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Biaxin - antibacterial agent of group of macroleads, semi-synthetic derivative of erythromycin. Biaxin is prescribed for treatment of infectious processes caused by flora, sensitive to it: sinusitis, pharyngitis, tonsillitis; folliculitis, streptoderma, erysipelatous inflammation, staphyloderma; bronchitis, community-acquired or hospital-acquired pneumonia; infections of dentoalveolar system; local or widespread mycobacterial infections caused by Mycobacterium intracellulare or Mycobacterium avium; in a complex of medicine oppressing acidity of a gastric acid for eradication of Helicobacter infection.
Dramamine is an antihistamine drug that reduces the effect of the natural chemical histamine in the body. Dramamine is used to treat or prevent the occurrence of nausea, vomiting, and dizziness associated with motion sickness.
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
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Anti-inflammatory gel for joints and muscles is based on plant components. Rumalaya gel is used for pain in the joints, muscles, relieves swelling and inflammation, makes the joints mobile. The gel is used in the treatment of damaged joints. Unlike tablets, it is used localized, thus gives the best result. The medicine is aimed to treat arthritis, polyarthritis, arthrosis, gout, injuries of the musculoskeletal system, bruises, sprains, rheumatic diseases, osteochondrosis, neuritis, and radiculitis.
Shallaki offers a herbal cure for sore joints and is based on an extract from Boswellia serrate. Completely natural origin of the medicine guarantees its safety and pure benefits for the body. It is a powerful auxiliary remedy applied in the treatment of arthritis as well as prevention of joint conditions. Shallaki alleviates pain and swelling in areas of inflammation and lowers the overall level of triglyceride and cholesterol with high efficiency. Its health-promoting behavior makes it a great aid for weight reduction.
Zudena is another representative of the PDE5 inhibitors ubiquitously used in contemporary urology. It is commonly used for the therapy and prevention of erectile dysfunction. The pills contain udenafil – a reverse inhibitor of the phosphodiesterase-5, which is responsible for filling the penis with blood. This active ingredient has a range of recently introduced advantages the most notable of which are more rapid absorption (30-60 minutes) and increased half-life (starting from 10 to 12 hours, which leads to a 24-hour period of activity). The medicine may be prescribed not only for symptomatic but also for a long-term treatment.
Imusporin 100 Capsule is an immunosuppressant. It works by suppressing your body’s immune response to help accept a newly transplanted organ (e.g., liver, kidney or heart). In rheumatoid arthritis, this immunosuppressive effect reduces inflammation (swelling) of joints and limits joint damage. In psoriasis, it works by reducing the activity of certain immune cells that cause overproduction of skin cells, thus improving scaling and redness.