It is used in the treatment of HIV infection in combination with an antiretroviral therapy in adults and children.
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Lamivudine product description
Lamivudine an antiviral agent, a nucleoside reverse transcriptase inhibitor, designed by Cipla ltd. Penetrating into cells, it is metabolized to 5-triphosphate, which suppresses the reverse transcriptase of HIV, which leads to an elimination of viral replication.
The pharmaceutical is prescribed during the recovery period after myocardial infarction, with the prevention of angina attacks.
Lamivudine safety information
Lamivudine is not desirable to take during pregnancy. The lactating women who take lamivudine should discontinue breastfeeding. It is forbidden to take this pharmaceutical product to people with hypersensitivity to lamivudine or other components of the remedy; with lactose sensitivity, lactase dearth, glucose-galactose malabsorption; with impaired renal function with creatinine clearance less than 30 ml/min.
Children under 3 years old, children weighing less than 14 kg - a significant contraindication. Lamivudine must be carefully assigned to people with the following maladies: renal failure with creatinine clearance from 30 ml/min to 50 ml/min, peripheral neuropathy (including in the history), pancreatitis (including in the anamnesis).
To prescribe lamivudine as a monotherapy is not recommended.
All the patients must be informed that the treating procedure with a help of antiretroviral pharmaceuticals, including lamivudine, does not exclude the risk of HIV transmission to other people withing sexual intercourse or blood transfusion. Therefore, all the people should take appropriate precautions.
In patients with impaired function of moderate and severe severity, lamivudine concentration in the blood plasma has grown due to a reduction in the clearance of lamivudine, therefore the adjustment of the dosage is required.
There was reported the high incidence of virological response and early resistance because of combining of lamivudine with tenofovir with dizoproxil fumarate and abacavir, as well as with tenofovir dizoproxil fumarate and didanosine in the dosing regimen once a day.
Lamivudine side effects
Among the unexpected side reactions: increasing the concentration of lactic acid in the serum; infrequently, hypertriglyceridemia, hypercholesterolemia, insulin resistance, a headache, insomnia, retching, queasiness, upper abdominal pain, diarrhea, rash, alopecia, arthralgia, muscle disorders, cough, nasal symptoms, fatigue, malaise, fever.
People receiving lamivudine or other antiretroviral medical remedies may gain opportunistic infections or other complications of HIV infection, so all the ill people must be closely controlled by a physician experienced in the medical care of patients with HIV-associated maladies.
Some ill people consuming lamivudine reported the rare manifestation of pancreatitis. However, it is not established whether this complication has been resulted by the pharmaceutical product or the underlying disease - HIV infection. The reception of this pharmaceutical must be quitted right away if the clinical symptoms or laboratory evidence of pancreatitis are detected (such as abdominal pain, queasiness, retching, or enlarged biochemical markers). It is necessary to quit the intake of the remedy prior the diagnosis of pancreatitis is excluded.
There have been reports of the detection in patients (predominantly in women) of lactic acidosis, severe hepatomegaly with steatosis, including fatal outcome due to antiretroviral therapy with nucleoside analogs in the form of separate pharmaceutical products, including lamivudine and its combinations.
Abilify is designed for patients with diagnosis named schizophrenia. It is used either during the exacerbation period or for maintenance treatment. Abilify is also prescribed in cases of an acute manic episodes of type 1 in manic-depressive psychosis, and as a supportive treatment for bipolar affective disorders. Abilify can be used as an additional treatment during depressive disorders. According to some experts, the drug can be used in order to treat alcoholism.
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Baclofen is a central muscle relaxant. It is assigned if the patient is diagnosed with spasticity in multiple sclerosis, strokes, craniocerebral trauma, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), with infantile cerebral palsy; alcoholism
Cefadroxil - cephalosporin antibiotic of the I generation for intake. It works as bactericidal, breaking synthesis of a cell wall of microorganisms. It has a broad spectrum of activity: it is active in relation as gram-positive (Staphylococcus spp. which don't produce and produce a penicillinase; Streptococcus spp. (including Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis), and gram-negative microorganisms (Shigella spp., Salmonella spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp., some strains of Proteus spp., especially Proteus mirabilis), Moraxella catarrhalis (Branhamella). Many strains of Enterococcus faecalis and Enterococcus faecium are steady against Cefadroxil.
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Epivir-HBV selectively suppresses replication of HIV-1 and HIV-2 in vitro. Gets into the cells induced by a virus passes into an active form - lamivudine 5 triphosphate which is the weak inhibitor of RNA and DNA-dependent return transcriptase of HIV.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
The drug is used for treatment of infectious diseases such as community acquired pneumonia, exacerbation of chronic bronchitis, acute sinusitis, pharyngitis and skin infections. The active ingredient in Omnicef is cefdinir—a semi-synthetic cephalosporin broad-spectrum antibiotic of the third generation for oral administration. Like other cephalosporin antibiotics, cefdinir has a bactericidal action against susceptible organisms through the inhibition of synthesis of bacteria peptidoglycan cell walls by interfering with the final stage of transamination, required for cross-linking.
Pamelor is a tricyclic antidepressant (TCA, tricyclic antidepressants) of the second generation. It is used in the treatment of some major depressive disorder and nocturnal enuresis (bedwetting) in children. In addition, the drug is sometimes used for the treatment of chronic diseases such as chronic fatigue syndrome, chronic pain and migraine, and the lability in certain neurological diseases.
An inhibitor of proton pump. The drug indications include: gastric ulcer and duodenal ulcer (in an acute phase), erosive gastritis, reflux-esophagit, Zolling-Erellison syndrome.
Teramycin acts depressingly on pathogens of many diseases, as well as biomycin. It is less toxic and longer preserves its action in the body. The medicine is used for the treatment of anthrax, teileriosis, cholera and pasteurellosis and other diseases.
Trimox has an active ingredient called amoxicillin. It is an antibiotic of penicillin, which fights bacteria. Trimox is used to treat many different types of infection caused by bacteria such as tonsillitis, bronchitis, pneumonia, gonorrhea and infections of the ear, nose, throat, skin or urinary tract. This remedy is sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a gastric acid reducer, called lansoprazole (Prevacid).
Zithromax - antibiotic of a wide spectrum of action. Antibiotic-azalide, a representative of a new subgroup of macrolide antibiotics. In the focus of inflammation it has a bactericidal effect. For the active ingredient of Zithromax, Azithromycin, all the gram-positive cocci (except those bacteria which are resistant to erythromycin) are susceptible.
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Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
Dostinex is used to treat hyperprolactinemia, which manifests as infertility, a violation of the menstrual cycle (oligomenorrhea, amenorrhea, anovulatory menstrual cycles), galactorrhea in women. Men use it to treat hyperprolactinemia, which manifests itself by a decrease in libido or impotence. The drug copes with micro- or macroprolactinoma, idiopathic hyperprolactinemia, syndrome of an empty Turkish saddle. It also suppresses physiological lactation after childbirth if the woman is unwilling or unable to breastfeed, or if there are contraindications to feeding for the child or the mother. The drug prevents lactation after childbirth in case of abortion or stillbirth.
Methotrexate belongs to the group of antimetabolites with cytostatic activity. It inhibits the conversion of dihydrofolic acid into tetrahydrofolic acid. Thymidylic acid and purine synthesis are disrupted, which, in turn, suppresses DNA synthesis and cell division. The maximum absorption of the medicine is observed after 30 to 60 minutes. The drug is metabolized by enzymes of the intestinal microflora, hepatocytes, and other cells.
It has a direct influence on muscles, mainly of arterial vessels over nitric receptor situated in blood vessels. Its active component is transformed into oxide in smooth muscles that effect prompts the activity of guanylate cyclases. It is crucial for the creation of cyclic guanosine monophosphate (relaxation mediator). The drug influence the processes in the central vascular system and heart activity. The nature and force of the influence of nitroglycerin on the cardiac organ and vessels depend on the cooperation of essential actions.
Beclomethasone nasal spray is used to relieve symptoms of sneezing, runny, stuffy, or itchy nose (rhinitis) caused by hay fever, other allergies, or vasomotor (nonallergic) rhinitis. It is also used to prevent nasal polyps (swelling of the lining of the nose) after nasal polyp removal surgery. Beclomethasone nasal spray should not be used to treat symptoms (e.g., sneezing, stuffy, runny, itchy nose) caused by the common cold. Beclomethasone nasal spray is in a class of medications called corticosteroids. It works by blocking the release of certain natural substances that cause allergy symptoms.
Cefaclor is a medicine used to treat the symptoms of various bacterial infections such as Bronchitis, Pharyngitis and Tonsillitis, Urinary Tract Infection, Ear Infections (Otitis Media) and Lower Respiratory Tract Infections. Cefaclor may be used alone or with other medications.
This product is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This product contains 2 medications: clonidine and chlorthalidone.
Elocon (mometasone furoate) Cream, 0.1% is a corticosteroid topical cream, lotion, or ointment indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 2 years of age or older.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below:
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