Asendin, which is amoxapine, is used at treatment of major depressive disorder. In comparison with other antidepressants, it has more quick start of action, at the same time its therapeutic effects are observed from four to seven days. The drug also has the properties similar to atypical anti-psychotics, and can be used not on direct treatment of schizophrenia. Asendin - is a tetracyclic antidepressant from a family of dibenzoxazepine, however the drug is often classified as tricyclic antidepressant - of secondary amines.
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Asendin product description
Asendin (Amoxapine) is a tricyclic antidepressant that is used to treat depressive disorders and dysthymia. Also, the drug is used in the treatment of panic disorders and bipolar personality disorders. Sometimes Asendin is prescribed to patients suffering from schizophrenia.
Asendin is used in the course of therapy of a major depressive disorder. Unlike other antidepressants, this drug acts faster; the effect can be noticed in 4 to 7 days after the start of therapy already. More than 80% of people treated with Asendin report that an effect is visible in two weeks.
Asendin is also indicated in the situations of anxiety states of neurotic genesis, including somatic pathology, with the effect of the action occurring quickly enough.
Asendin safety information
Like all other antidepressants, Asendin can potentially enlarge the opportunity of suicidal thoughts or attitude in teenagers, adolescents and young people under the age of 25 years. Its use is also not allowed to persons with hypersensitivity to amoxapine or other components of the pharmaceutical. Its use is also forbidden in case of the existence of the next diseases: severe cardiovascular diseases (the potential for cardiotoxic side conditions, such as prolongation of the QT interval); uncorrected angle-closure glaucoma; acute post-infarction syndrome;
Using Asendin with other antidepressants is also prohibited. If you are taking any other medical substances, be sure to consult with your doctor before starting the course of taking remedy with Asendin.
Therapists do not allow to use of Amoxapine (the main component of Asendin) for breastfeeding women since the pharmaceutical product is excreted in breast milk.
Don’t use Asendin with alcohol it is very serious damage for life!
Overdose
The substance is considered particularly toxic in case of an overdose. Its use is connected with a high risk of renal failure (developing within 2-5 days), coma, seizures and even epileptic status. Some people believe that the substance is less cardiotoxic in an overdose than other tricyclic antidepressants, although there are data on cardiotoxic overdoses. That is the reason to be absolutely careful in the period of taking the remedy.
Asendin side effects
Despite the apparent lack of extrapyramidal side conditions in persons with schizophrenia, it was found that the pharmaceutical product causes an exacerbation of motor illnesses in people with psychosis of Parkinson's disease.
The pharmaceutical produces less anticholinergic, sedative issues and brings less weight gain than some of the earlier tricyclic antidepressants.
The side situations of taking Asendin can be the following:
constipation; dry mouth; sedation; alarm; ataxia; blurred vision; confusion; dizziness; a headache; fatigue; nausea nervousness/anxiety; excessive appetite; rash; increased sweating (sweating); tremor; heartbeat; nightmares; excitement; weakness; changes in the ECG; puffiness; an increase of the level of prolactin.
To prevent more serious side effects, consult a physician before starting treatment.
Anafranil, which is clomipramine - is a tricyclic antidepressant. Clomipramine has antiserotonin effect, it eliminates night enuresis, causes loss of appetite. Sedative action is shown due to linkng with H1-histamine receptors, blocking of alpha-adrenoceptors. Medicine eliminates arrhythmia, slows down ventricular conductivity. The anti-depressive effect is implemented due to increase in concentration of noradrenaline, serotonin in synapses because of weakening of the process of recapture of these substances by presynaptic neurons.
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Antabuse - the medicine for treatment of alcoholism. The effect of medicine is implemented due to blockade of acetaldehydehydrogenaz which takes part in ethanol metabolism in consequence of which rises the level of acetaldehyde which causes a number of negative symptoms (including hot flashes, hyperemia of face, vomiting, tachycardia and increase in pressure). These effects arising after alcohol intake lead to development of cause-effect relations and rejections of alcohol intake. Thus, the patient has a conditioned-reflex disgust for a smell and taste of alcohol.
Betapace - beta adrenoblocker, antiarrhytmic medicine. It is taken for treatment of ventricular arrhythmia, tachycardia, supraventricular arrhythmia, tachycardia at thyrotoxicosis, angina of effort, especially at combination with tachyarrhythmias, arterial hypertension, hypertrophic cardiomyopathy, prolapse of the mitral valve, prevention and treatment of myocardial infarction at stable condition of the patient.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Cardizem, derivative benzothiazepine, has anti-anginal, antiarrhytmic and hypotensive effect. It is prescribed at arterial hypertension: after myocardial infarction, at patients with accompanying stenocardia when beta adrenoblockers, are contraindicative at patients with diabetic nephropathy, in cases when ACE inhibitors are contraindicated; angina of effort, Prinzmetal's angina; prevention of a coronary spasm when carrying out a coronary angiography or operation of aortocoronary shunting.
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
BCCC; a derivative of diphenylalkylamine. Has antianginal, anti-arrhythmic and hypotensive effect. The antianginal effect is associated with both direct action on the myocardium and with the effect on peripheral hemodynamics. It is prescribed with stenocardia, supraventricular tachycardia, sinus tachycardia, ciliary tachyarrhythmia, atrial flutter, atrial extrasystole, arterial hypertension, GOKMP, primary hypertension in the "small" circle of the circulation.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
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Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Starlix - an oral synthetic hypoglycemic drug. A medicine based on nateglinide for the treatment of diabetes, which helps to control blood sugar levels. This medicine helps your body to react better to the insulin produced by your pancreas.
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Verapamil is a calcium channel blocker, it treats high blood pressure relaxing and widening blood vessels.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
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Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
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