Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
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Adalat product description
Drug uses
Adalat is recommended to treat adult patients characterized by calcium atoms flow from the extracellular compartment to the artery cells associated with serious cardiac and vascular pathologies, such as:
- Disorders in the blood flow to the left atrium
- High blood pressure in the vessels
The mechanism of Adalat action involves relaxation of the blood vessel walls and blood flow improvement. Adalat is characterized by the fact that this anti-hypertensive agent does not affect a heartbeat.
An adequate drug application reduces pain feeling in the chest. To protect the heart, the large and small arteries, 20 and 40 mg of Adalat should be taken daily divided in two or three doses. Gradually, the daily Adalat dosage can be increased to 80 mg equally separated.
The dosing regimen is required to be adjusted under the combined treatment of hypertension, cerebrovascular disease, and low body weight.
Missed dose
Adalat pills should be taken with 2-3 hour gap between doses. If the patient takes drug 2-3 times a day at equal intervals, minor changes in the dosing regimen are allowed. If the pill intake was missed, and it is the time for the next dose, the missed pill is better to be skipped.
More information
Grapefruit juice can significantly change (increase) the pharmacodynamic properties of Adalat, so it is not recommended while taking this antihypertensive agent.
Storage
Calcium channel blocker Adalat should be stored in its original package at room temperature up to 30°C. Do not use broken or crashed pills. Protect from moisture and direct sunlight.
Adalat safety information
Warnings
Some categories of patients should take antihypertensive agent Adalat with extra caution, like, for example, the seniors, or patients with metabolic disorders (diabetes) and liver diseases (hepatitis, Budd-Chiari syndrome, and steatosis). Adalat use with drugs affecting the blood pressure (for example, Prozac, Synercid, Tagamet, and Eryc) may require the dosing regimen to be adjusted.
Disclaimer
The medical and healthcare information on the antihypertensive therapy and Adalat is intended to be used as an information resource only and should not be used for diagnostic, prognostic, and therapeutic purposes as a substitute for the cardiologist’s consultation. Using this review of Adalat as an information resource, you agree that the online pharmacy shall not be responsible for any of your actions and consequences of actions based on the use or non-use of the provided information on Adalat.
Adalat Side Effects
All adverse reactions caused by Adalat action are mild and not threatening to the patient’s health. The most common adverse reactions arisen from the use of the antianginal drug include malaise, headache, dizziness, edema, fatigue /asthenia, vasodilation, nausea, and constipation.
Sometimes such adverse reactions as mood changes, paranoid syndrome, taste perversion, anemia, arthritis, fever, nervousness, and syncope are reported as well. Few cases of gynecomastia and angioedema have been revealed in elderly patients.
Rare adverse reactions after the antianginal drug therapy were reported according to post-marketing experience. Actually, all of them were insignificant and passed in a while. Some patients taking Adalat are reported to experience irritation of the stomach and insomnia.
Asacol, which is mesalamine - derivative of 5-aminosalicylic acid. It is prsecribed for treatment and remission maintenance at patients with ulcer colitis (earlier known as nonspecific ulcer colitis) of mild and moderate type.
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Benicar is a drug that is prescribed for essential arterial hypertension. In case of arterial hypertension, olmesartan causes a dose-dependent long-term reduction of a blood pressure.
Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
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Nootropilum affects the CNS, by changing the speed of propagation of the excitation in the brain, improves metabolic processes in nerve cells, improves by acting on the rheological characteristics of blood and causing no vasodilatory action.
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Teramycin acts depressingly on pathogens of many diseases, as well as biomycin. It is less toxic and longer preserves its action in the body. The medicine is used for the treatment of anthrax, teileriosis, cholera and pasteurellosis and other diseases.
Xenical - a powerful, specific and reversible inhibitor of gastrointestinal lipases, which has a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine portion of the gastric and pancreatic lipases. The inactivated enzyme at the same time loses the ability to break down food fats coming in the form of triglycerides, to sucking free fatty acids and monoglycerides. Since uncleaved triglycerides are not absorbed, the resulting decrease in the intake of calories into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.
Zantac - ranitidin - the drug is intended for the treatment of duodenal ulcers, benign gastric ulcer, postoperative ulcer, reflux esophagitis, Zollinger-Ellison syndrome, epigastric or chest pain. The administration of ranitidine is indicated in cases where a decrease in gastric secretion and a decrease in the production of hydrochloric acid is desirable, for the prevention of gastrointestinal bleeding, for the prevention of recurrence of bleeding in patients with bleeding ulcers of the stomach and duodenum, before general anesthesia in patients with a presumed risk of aspiration of acidic stomach contents (Mendelssohn syndrome), especially in women during childbirth delivery clashes.
Zocor is indicated to reduce mortality due to coronary artery disease. It is prescribed for the reduction of risk of serious vascular and coronary complications: non-fatal myocardial infarction, coronary death, stroke; revascularization operations. Designed to reduce the risk of the need for coronary blood flow restoration; rot reduce the risk of the need for surgical intervention to restore peripheral blood flow and other types of non-coronary revascularization; to reduce the risk of hospitalization in connection with attacks of angina pectoris; to decrease in the elevated level of total cholesterol, LDL cholesterol, triglycerides. apolipoprotein B; for increasing HDL cholesterol in patients with primary hypercholesterolemia, including heterozygous familial hypercholesterolemia.
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Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Product description
Alfacip is an active metabolite of Alfacip, which performs important functions in regulation of the calcium balance and the bone metabolism. (Hypocalcemia; Osteodystrophy; secondary hyperparathyroidism;)
