Pharmacological influence of Calan is explained by braking of a flow of calcium ions through the slowed-down calcic tubules of cellular covers of smooth muscle structure of vessels and a cardiac muscle. Calan is prescribed if it was diagnosed paroxysmal supraventricular tachycardia (except WPW syndrome), sinus tachycardia, premature atrial contraction, blinking and atrial flutter, stenocardia (inc. stress, postinfarction), arterial hypertension, hypertensive crisis, idiopathic hypertrophic subaortic stenosis, hypertrophic cardiomyopathy.

Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.

"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.

A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.

A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.