A peripheral vasodilator, blocks postsynaptic alpha1-adrenergic receptors and prevents the vasoconstrictive influence of catecholamines. It reduces pressure in the pulmonary veins and the right atrium significantly, it also reduces pulmonary vascular resistance moderately. The drug therapeutic indications include: arterial hypertension; CHF (in combination therapy), Raynaud's syndrome and disease, pheochromocytoma, peripheral vascular spasm on the background of poisoning with ergot alkaloids. Prostatic hyperplasia

A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.